How do I lose weight in 2 weeks naturally? To lose weight, you have to be able to burn more calories than you consume. To lose one pound, you need to be in a calorie deficit of 3,500. I know, this sounds overwhelming. But there are ways for you to be in a calorie deficit without starving yourself and without giving up your favorite foods, which is what I did . So to lose weight naturally and safely in two weeks, there are a few things you can do: exercise in the morning and on an empty stomach – it enables fat burning processes drink a gallon of water throughout the day – because drinking water burns calories avoid crash diets – they are unhealthy and ineffective in the long-run don’t stress – because when stressed you crave sugar